After being a heavy favorite in each of their first two games of the year, Michigan State football has opened as a two-point underdog to Washington in Week 3.The over-under total opened at 54 Elijah Mitchell Jersey .5 points for the matchup.The Spartans (2-0) took down a pair of Mid-American Conference opponents, Western Michigan and Akron, in Week 1 and 2, but now must prepare for a West Coast road trip to face a Pac-12 foe.The Huskies have also opened 2-0 to start their 2022 campaign, with wins over Kent State and Portland State in the first two Arik Armstead Jersey weeks.Scroll to ContinueMichigan State was one of the best programs against the spread in 2021, finishing 9-3-1 against the number a year ago. The Spartans also had four wins outright as an underdog last season.So far in 2022, Michigan State is 2-0 against the spread. The Spartans werefavored by 21.5 Bruce Ellington Jersey points against Western Michigan and beat the Broncos by 22, and MSU was favored by 34.5 against Akron and won, 52-0.Washington looks improved under first-year head coach Kalen DeBoer, albeit against two overmatched opponents. The Huskies will attack Michigan State's secondary with an improved pa sing attack and a dual-threat quarterback in Michael Penix Jr. who transferred to Washington from Indiana.Michigan opened as a 45-point favorite over UConn, as the Wolverines continue their stroll through one of the weakest non-conference schedules among Power 5 programs.Nebraska Deebo Samuel Jersey is a 16-point underdog at home vs. Oklahoma.Notre Dame opened as an 11-point favorite over California (2-0), despite an 0-2 start to the season for the Fighting Irish.Penn State is a three-point favorite on the road at Auburn.Oregon opened as a three-point favorite over BYU. The Ducks are ranked No. 25 in this week's AP Poll, while the Cougars come in ranked No. 12 in the nation.Coming off an upset lo s to Appalachian State, Texas A&M opened as a five-point favorite vs. Miami in College Station.Ohio State is Jerry Rice Hoodies Sweatshirts a 34-point favorite over Toledo at home in Columbus.