When negotiating the cost of a clinical trial with a Contract Research Organization, it is important to consider a number of factors. For example, some sponsors may hold back a significant portion of the payment until the trial is completed. This could be as much as 10% of the total budget.

Another factor is the fact that not every subject will complete the study. If this is the case, the budget should be adjusted to account for this possibility. The size and complexity of clinical trials has increased considerably over the last decade. In addition to a growing number of trial sites and therapeutic areas, the process is increasingly global.

For example, it costs an average of $2.6 billion to bring a new drug to market in the U.S. The majority of this money is spent on human clinical trials. The most crucial phase of the process, called Phase III, can require as many as hundreds of subjects. Trial costs also vary widely. The Contract Research Organization most expensive clinical trials are typically those involving pain and anesthesia, ophthalmology, and gastroenterology.

The cheapest trials typically involve anti-infective treatments. However, the cost of a pivotal trial may range from US$19 million to US$33 million. A Contract Research Organization can help biopharmaceutical companies reduce costs associated with clinical trials. These organizations have large databases of volunteers, making them an ideal choice for conducting research.

Additionally, Contract Research Organization can assist in obtaining the data needed to support the clinical trials. These organizations can even help with recruitment of patients.

The Biomedical R&D Price Index tracks the costs of clinical trials. This index is based on NIH-funded research at academic medical centers. It is a measure of the cost of biomedical research in the U.S.