Levodopa and the Progression of Parkinson's Disease BACKGROUND
Despite the known benefit of Levodopa in reducing the symptoms of Parkinson's disease, concern has been expressed that its use might hasten neurodegeneration. This study assessed the effect of Levodopa on the rate of progression of Parkinson's disease.
METHODS
In this randomized, double-blind, placebo-controlled trial, we evaluated 361 patients with early Parkinson's disease...