Levodopa and the Progression of Parkinson's Disease
BACKGROUND Despite the known benefit of Levodopa in reducing the symptoms of Parkinson's disease, concern has been expressed that its use might hasten neurodegeneration. This study assessed the effect of Levodopa on the rate of progression of Parkinson's disease.   METHODS In this randomized, double-blind, placebo-controlled trial, we evaluated 361 patients with early Parkinson's disease...
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